Endo H (Endoglycosidase H)

Endo H (Endoglycosidase H) is a highly specific glycosidase used for the removal of high-mannose and some hybrid N-linked glycans from glycoproteins. By cleaving the bond between the two N-acetylglucosamine (GlcNAc) residues in the glycan core, Endo H leaves one GlcNAc attached to the asparagine residue. This precise action makes Endo H indispensable for studying glycosylation, monitoring protein folding, and performing structural biology experiments.